Kim Goodsell

The actualized ‘genomified’, quantified, digitalized “patient of the future."

Author of Gaming Aging in the “Omic” Era, Kim’s foray into twenty-first–century molecular research has been credited by Dr. Eric Topol, one of the world’s foremost biomedical scientists, physicians and visionary leaders as “marking an important watershed moment in medicine made possible by the proliferation of digital technology and the online democratization of information”.

With the advent of New Generation High-Throughput Sequencing, CRISPR, RNA-Seq and other emerging technologies medical research is being redefined by it’s quantum leap into the study of “omes”—genome, transcriptome, proteome, metabolome, epigenome, patientome; the big data its generating; the information technology that handles it and analytical software which interprets it. Its clinical translation promises to replace “population medicine” with personalized precision programmatic multimodal metabolic therapeutics. Early applications of these precision approaches in the treatment of the most dreaded complex degenerative diseases associated with aging— heart disease, cancer, diabetes and dementia; are reporting unheard of success. We are beginning to realize not only the possibility of effective therapeutics which extend the “health span” of individuals, but the repair of the genes and regulatory networks which anticipate cures.

The fury of hyper-innovative digital technology is extending not only the frontiers of medical research, but self-knowledge. Ubiquitous connectivity and the online democratization of information has precipitated a shift in the power and organizational structure of medicine. It has spawned a “digital patient revolution”– likely the most profound disruption in the history of healthcare. In a matter of a decade patients have gone from not having access to their data … to generating it … to owning it … to participating in the co-production of medical intelligence. Kim is a medical research investigator. Her field of investigation is the molecular biology of aging. Her focus is on the LMNA gene’s interaction with the key growth and longevity genes regulating aging. She is considered an expert in LMNA-mediated cardiomyopathy and heart failure phenotypes. Mutations in the LMNA gene are responsible for the most dramatic form of premature aging— Hutchinson-Gilford progeria syndrome; as well as a diverse spectrum of rare complex premature aging phenotypes which mimic common age-related degenerative chronic diseases, and model the biomolecular activities of normal aging. Understanding the “omics” of this rare gene mutation has far-reaching implications extending into the field of human longevity and aging.

Kim’s work has been featured at the Heart Rhythm Society’s Annual Scientific Sessions and published in the Journal of Cardiovascular Electrophysiology. She is a peer-review referee and editorial writer for Circulation Research— Journal of the American Heart Association. As founder of Perfecting the Art of Aging— a longevity consulting concern providing personal research services; Kim works in collaboration with her clients and MPI Cognition to devise precise personalized prevention, management, and reversal strategies aimed at gaming aging.

Kim is not an MD or a PhD. Kim is a rare disease patient with a LMNA mutation. Her only degree is from the infamous “Google School of Medicine”. Her debut appearance at the 2014 Future of Genomic Medicine conference made headline news announcing— “The patient from the future, here today”. Her story: DIY diagnosis: how an extreme athlete uncovered her genetic flaw; was subsequently published in National Geographic- Phenomena, Mosaic- the science of life, The BBC, The Atlantic and other major publications.

At the epicenter of the medical community’s debate on the dangers and advantages of giving power to the people to direct and take control of their healthcare, Kim co-stars with Angelina Jolie in the “Medical Blockbuster Book Of The Year”: The Patient Will See You Now – The Future of Medicine is in Your Hands. Raising the expectations of the patient across the complex medical community of physicians, industry, regulatory and policy leaders, Kim is a frequent speaker and participant in medical policy advisory groups and think tanks.

Defying the medical profession’s expectations of today’s “google and go” patient, Kim has won international acclaim and high praise as a “unique”, “one-of-a-kind”, “extraordinary” patient— accolades she adamantly rejects as socially disempowering; concealing an implicit suggestion that she is an outlier and will continue to be. As Dr. Topol warns in the Medscape article: Patient Cracks Her Own Mysterious Dual Diagnosis, “there will be a lot more patients like Kim. Millions of people will have their genome sequenced. If doctors don’t get ‘genomified,’ their patients will.” Kim takes you down the rabbit hole and through the looking glass as she remembers the future. The future is here now … don’t be late.

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